Insulinoma is a rare tumour of the Pancreas which produces excess insulin leading to very low sugar levels .Most of them are found to be benign, but rarely some can become malignant. These are rare with an estimated incidence of 1 to 4 cases per million people per year.It is seen more in women and often get diagnosed in the age groups of 40-60 years. It can occur associated with multiple endocrine neoplasia (MEN-1 syndrome) a genetic condition affecting multiple endocrine glands.
Symptoms include
1.Undue tiredness due to repeated low sugar levels
2.Irritablity and difficulty in concentration
3.Anxiety
4.Blurring of vision
5.Slurring of speech
6.In severe cases it can lead to unconsciousness or seizures.
We can detect this condition by conducting a supervised prolonged 72 hour fasting test where we can find out the blood glucose fluctuations and take samples for insulin and C peptide levels. By doing imaging studies like CT scan, MRI scan or specialized PET scan we can confirm the diagnosis and take further steps to treat it. Usually surgical removal is done as part of the treatment.Dietary adjustments including small frequent meals with high protein and fiber are recommended.
Dr. Deepa G, MHSc (Diab), Dip (Diab)